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Innovative serum is free from harsh ingredients & formulated with plant-based extracts & Avène Thermal Spring Water to help reduce excess oil & appearance of blemishes for visibly clearer skin in as soon as 7 days.
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OVER $75
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US FRENCH PHARMACY
OVER $75
WITHIN THE US
SOURCING
WITH THIS PRODUCT!
US FRENCH PHARMACY
This lightweight, water-gel serum is specially designed for oily and acne-prone skin, combining a minimalist blend of just 11 targeted actives—including patented Comedoclastin™ from milk thistle extract—to visibly reduce excess oil, tighten pores, and diminish blemishes.
Powered by calming Avène Thermal Spring Water and silica for a shine-free matte finish, it revitalizes the skin’s balance, visibly clarifying the complexion in as little as seven days. The fragrance‑ and silicone-free formula offers lasting results without irritation and can be used alone or added to a medicated acne regimen.
Formulated with only 11 blemish fighting ingredients
Helps restore and re-establish a healthy skin environment
Long-lasting results to help visibly reduce appearance of blemishes
Apply morning and evening to the face after cleansing with a Cleanance cleansing product.
Cleanance Concentrate can be used alone or in combination with a non-drying medicinal treatmen
COMEDOCLASTINTM:
Stabilized extract derived from Milk thistle helps visibly reduce and limit appearance of blemishes
SILICA:
Helps absorb excess oil for a shine-free matte finish
AVENE THERMAL SPRING WATER:
Clinically shown by 150 studies to soothe, soften and calm the skin
+ AVENE THERMAL SPRING WATER (AVENE AQUA), ISOPROPYL ALCOHOL, PEG-6, GLYCERIN, SILYBUM MARIANUM FRUIT EXTRACT, SILICA, POLYACRYLATE-13, POLYISOBUTENE, POLYSORBATE 20, SORBITAN ISOSTEARATE, WATER (AQUA)
At the heart of the brand is Avène Thermal Spring Water, a natural soothing source clinically shown by over 150 studies to soothe, soften and calm the skin.
Originating as pure rain mixed with sea-spray rich in mineral salts, Avène Thermal Spring Water makes its 50-year journey through the Cévennes Mountains in Avène, France.
Containing unique combinations of trace minerals from this journey, Avene products deliver the Water completely intact, pure and clear, as if you were drawing it directly from the spring.
For those who want to get even closer, the Avene Hydrotherapy Center offers cutting-edge dermatological science and therapy combined with the world-renowned quality and efficiency of its thermal water.
As one of the many ways to give back, Avene Laboratories launched One Smile - an inititative to improve the quality of life for oncology patients through the use of dermo-cosmetic treatments.
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Thank you very much, for amazing cream! Works very well, skin look’s more firm and rejuvenated and soft. And deduce fine lines from even first time to used. I am happy to have that magic cram it is my favorite now!!😄 Elvira USA 06/27/25
Beautiful glow for normal to dry skin. I'm age 47.5 and love this spf. Only the one made in France. No irritation and goes on smooth and clear. Highly recommend.
I am a flight attendant and I am 50 percent French. I was off two years with a back injury and terrified I could not get the French recipe for this. It is just as I if I bought it in France. Im going back to work this month and will be thrilled to pay 6 euro but it is worth every cent at any cost. Love you French pharmacy. I am 53 and thanks to French genetics and this product I get accused of being much younger. Nothing beats French products and this is the Holy Grail.
I bought A313 when I was in France and thought it was too greasy. I am enjoying this product a lot more and it has made my skin feel very silky. I am starting to see the fine lines disappear around my mouth area. This 57yo would highly recommend.
I just started using the product about a week ago, I have noticed a softness with my lines on my cheeks and around my mouth. I am 61 years old, so it’s always exciting when you see that kind of softness.